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Critically Speaking

Jan 15, 2020

Ever heard of Glyphosate? 


If not, it's likely you've heard of the product "Roundup", the weed killer.  It's been in the news a lot because jurors in three separate trials have agreed that exposure to Roundup caused plaintiff's non-Hodgkin’s lymphoma and awarded a total of $2.4 billion in compensation and punitive damages against its manufacturer.  New dangers now appear to be presenting themselves.  A condition known as non-alcoholic fatty liver disease, which increases risks of cirrhosis and liver cancer, is on the rise, as are deaths from the disease. Investigators at the University of California at San Diego School of Medicine have recently reported an association between glyphosate, the ingredient in Roundup, and this serious liver disease.  In today's episode, Therese and Dr. Paul Mills, one of the authors of the study, discuss the evidence for this association. 


Key Takeaways:  

  • Glyphosate and its metabolite aminomethylphosphonic acid (AMPA) are detectable in urine, and their levels have been increasing over time. 
  • Prior to the introduction of Genetically Modified Crops, and the agricultural use of Roundup, it was practically non-detectable in humans. 
  • Glyphosate residue was higher in the urine of subjects with liver disease regardless of possible underlying factors such as age, body mass index, or race. 


"Glyphosate, as you must know, it's only just one of so many other herbicides and insecticides and fungicides also used on crops. So we've been exposed to hundreds of novel compounds that we weren't evolved and designed to really deal with and process metabolically and otherwise." —  Dr. Paul Mills 


Connect with Dr. Paul Mills: 

UCSD Profile: Paul J. Mills    


Connect with Therese:  


Twitter: @CritiSpeak  




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